Publications

Zhang, Y., Sung, H.-H., Ziegler, A. B., Wu, Y.-C., Viais, R., Sánchez-Huertas, C., Kilo, L., Agircan, F. G., Cheng, Y.-J., Mouri, K., Uemura, T., Lüders, J., Chien, C.-T., & Tavosanis, G. (2024). Augmin complex activity finetunes dendrite morphology through non-centrosomal microtubule nucleation in vivo. Journal of Cell Science, 137(9), jcs261512. https://doi.org/10.1242/jcs.261512

Gallisà-Suñé, N., Sànchez-Fernàndez-de-Landa, P., Zimmermann, F., Serna, M., Regué, L., Paz, J., Llorca, O., Lüders, J., & Roig, J. (2023). BICD2 phosphorylation regulates dynein function and centrosome separation in G2 and M. Nature Communications, 14(1), 2434. https://doi.org/10.1038/s41467-023-38116-1

Lüders, J. (2023). Microtubule cytoskeleton: The centrosome gains a membrane. Current Biology: CB, 33(5), R180–R182. https://doi.org/10.1016/j.cub.2023.02.011

Ali, A., Vineethakumari, C., Lacasa, C., & Lüders, J. (2023). Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG. Nature Communications, 14(1), 289. https://doi.org/10.1038/s41467-023-35955-w

Dutto, I., Gerhards, J., Herrera, A., Souckova, O., Škopová, V., Smak, J. A., Junza, A., Yanes, O., Boeckx, C., Burkhalter, M. D., Zikánová, M., Pons, S., Philipp, M., Lüders, J., & Stracker, T. H. (2022). Pathway-specific effects of ADSL deficiency on neurodevelopment. ELife, 11, e70518. https://doi.org/10.7554/eLife.70518

Vineethakumari, C., & Lüders, J. (2022). Microtubule Anchoring: Attaching Dynamic Polymers to Cellular Structures. Frontiers in Cell and Developmental Biology, 10, 867870. https://doi.org/10.3389/fcell.2022.867870

Lovera, M., & Lüders, J. (2021). The ciliary impact of nonciliary gene mutations. Trends in Cell Biology, 31(11), 876–887. https://doi.org/10.1016/j.tcb.2021.06.001

Schweizer, N., Haren, L., Dutto, I., Viais, R., Lacasa, C., Merdes, A., & Lüders, J. (2021). Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold. Nature Communications, 12(1), 6042. https://doi.org/10.1038/s41467-021-26252-5

Viais, R., Fariña-Mosquera, M., Villamor-Payà, M., Watanabe, S., Palenzuela, L., Lacasa, C., & Lüders, J. (2021). Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development. ELife, 10, e67989. https://doi.org/10.7554/eLife.67989

Schweizer, N., & Lüders, J. (2021). From tip to toe - dressing centrioles in γTuRC. Journal of Cell Science, 134(14), jcs258397. https://doi.org/10.1242/jcs.258397

Parcerisas, A., Pujadas, L., Ortega-Gascó, A., Perelló-Amorós, B., Viais, R., Hino, K., Figueiro-Silva, J., La Torre, A., Trullás, R., Simó, S., Lüders, J., & Soriano, E. (2020). NCAM2 Regulates Dendritic and Axonal Differentiation through the Cytoskeletal Proteins MAP2 and 14-3-3. Cerebral Cortex (New York, N.Y.: 1991), 30(6), 3781–3799. https://doi.org/10.1093/cercor/bhz342

Ezquerra, A., Viais, R., & Lüders, J. (2020). Assaying Microtubule Nucleation. Methods in Molecular Biology (Clifton, N.J.), 2101, 163–178. https://doi.org/10.1007/978-1-0716-0219-5_11

Freixo, F., Martinez Delgado, P., Manso, Y., Sánchez-Huertas, C., Lacasa, C., Soriano, E., Roig, J., & Lüders, J. (2018). NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization. Nature Communications, 9(1), 2330. https://doi.org/10.1038/s41467-018-04706-7

Lüders, J. (2018). XMAP215 joins microtubule nucleation team. Nature Cell Biology, 20(5), 508–510. https://doi.org/10.1038/s41556-018-0100-9

Paz, J., & Lüders, J. (2018). Microtubule-Organizing Centers: Towards a Minimal Parts List. Trends in Cell Biology, 28(3), 176–187. https://doi.org/10.1016/j.tcb.2017.10.005

Sánchez-Huertas, C., Freixo, F., Viais, R., Lacasa, C., Soriano, E., & Lüders, J. (2016). Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity. Nature Communications, 7, 12187. https://doi.org/10.1038/ncomms12187

Lecland, N., & Lüders, J. (2016). Imaging and Quantifying the Dynamics of γ-Tubulin at Microtubule Minus Ends in Mitotic Spindles. Methods in Molecular Biology (Clifton, N.J.), 1413, 63–75. https://doi.org/10.1007/978-1-4939-3542-0_5

Marjanović, M., Sánchez-Huertas, C., Terré, B., Gómez, R., Scheel, J. F., Pacheco, S., Knobel, P. A., Martínez-Marchal, A., Aivio, S., Palenzuela, L., Wolfrum, U., McKinnon, P. J., Suja, J. A., Roig, I., Costanzo, V., Lüders, J., & Stracker, T. H. (2015). CEP63 deficiency promotes p53-dependent microcephaly and reveals a role for the centrosome in meiotic recombination. Nature Communications, 6, 7676. https://doi.org/10.1038/ncomms8676

Comartin, D., Gupta, G. D., Fussner, E., Coyaud, É., Hasegan, M., Archinti, M., Cheung, S. W. T., Pinchev, D., Lawo, S., Raught, B., Bazett-Jones, D. P., Lüders, J., & Pelletier, L. (2013). CEP120 and SPICE1 cooperate with CPAP in centriole elongation. Current Biology: CB, 23(14), 1360–1366. https://doi.org/10.1016/j.cub.2013.06.002

Brown, N. J., Marjanović, M., Lüders, J., Stracker, T. H., & Costanzo, V. (2013). Cep63 and cep152 cooperate to ensure centriole duplication. PloS One, 8(7), e69986. https://doi.org/10.1371/journal.pone.0069986

Lüders, J. (2012). The amorphous pericentriolar cloud takes shape. Nature Cell Biology, 14(11), 1126–1128. https://doi.org/10.1038/ncb2617

Teixidó-Travesa, N., Roig, J., & Lüders, J. (2012). The where, when and how of microtubule nucleation - one ring to rule them all. Journal of Cell Science, 125(Pt 19), 4445–4456. https://doi.org/10.1242/jcs.106971

Estruch, S. B., Buzón, V., Carbó, L. R., Schorova, L., Lüders, J., & Estébanez-Perpiñá, E. (2012). The oncoprotein BCL11A binds to orphan nuclear receptor TLX and potentiates its transrepressive function. PloS One, 7(6), e37963. https://doi.org/10.1371/journal.pone.0037963

Teixidó-Travesa, N., Villén, J., Lacasa, C., Bertran, M. T., Archinti, M., Gygi, S. P., Caelles, C., Roig, J., & Lüders, J. (2010). The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8. Molecular Biology of the Cell, 21(22), 3963–3972. https://doi.org/10.1091/mbc.E10-05-0408

Archinti, M., Lacasa, C., Teixidó-Travesa, N., & Lüders, J. (2010). SPICE--a previously uncharacterized protein required for centriole duplication and mitotic chromosome congression. Journal of Cell Science, 123(Pt 18), 3039–3046. https://doi.org/10.1242/jcs.069963

Haren, L., Stearns, T., & Lüders, J. (2009). Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components. PloS One, 4(6), e5976. https://doi.org/10.1371/journal.pone.0005976

Lüders, J., & Stearns, T. (2007). Microtubule-organizing centres: a re-evaluation. Nature Reviews. Molecular Cell Biology, 8(2), 161–167. https://doi.org/10.1038/nrm2100

Lüders, J., Patel, U. K., & Stearns, T. (2006). GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nature Cell Biology, 8(2), 137–147. https://doi.org/10.1038/ncb1349

Lüders, J., Pyrowolakis, G., & Jentsch, S. (2003). The ubiquitin-like protein HUB1 forms SDS-resistant complexes with cellular proteins in the absence of ATP. EMBO Reports, 4(12), 1169–1174. https://doi.org/10.1038/sj.embor.7400025

Lüders, J., Demand, J., Papp, O., & Höhfeld, J. (2000). Distinct isoforms of the cofactor BAG-1 differentially affect Hsc70 chaperone function. The Journal of Biological Chemistry, 275(20), 14817–14823. https://doi.org/10.1074/jbc.275.20.14817

Lüders, J., Demand, J., & Höhfeld, J. (2000). The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome. The Journal of Biological Chemistry, 275(7), 4613–4617. https://doi.org/10.1074/jbc.275.7.4613

Möller, G., Lüders, J., Markus, M., Husen, B., Van Veldhoven, P. P., & Adamski, J. (1999). Peroxisome targeting of porcine 17beta-hydroxysteroid dehydrogenase type IV/D-specific multifunctional protein 2 is mediated by its C-terminal tripeptide AKI. Journal of Cellular Biochemistry, 73(1), 70–78. https://doi.org/10.1002/(sici)1097-4644(19990401)73:1<70::aid-jcb8>3.0.co;2-k

Lüders, J., Demand, J., Schönfelder, S., Frien, M., Zimmermann, R., & Höhfeld, J. (1998). Cofactor-induced modulation of the functional specificity of the molecular chaperone Hsc70. Biological Chemistry, 379(10), 1217–1226. https://doi.org/10.1515/bchm.1998.379.10.1217

Demand, J., Lüders, J., & Höhfeld, J. (1998). The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors. Molecular and Cellular Biology, 18(4), 2023–2028. https://doi.org/10.1128/MCB.18.4.2023